Waters BioAccord LC-MS System

Mass Accuracy

Intact Mass Analysis: <20 ppm (top 3 Glycoform peaks), <5 ppm (mass precision)
Peptide Mapping: <10 ppm (precursor mass accuracy)
Released Glycan Analysis: 5 ppm mass filter

Resolution

High resolution (oa-Tof mass analyzer)

Sensitivity

Peptide Mapping: >3 orders of intensity (identified peptides)
Released Glycan Analysis: >0.5% of the total (relative abundance for identification)

Speed

Up to 80 Hz (optical detectors)

Dynamic Range

3 orders of intensity (identified peptides in peptide mapping)