Waters RADIAN ASAP Direct Mass Detector

Mass Accuracy

Not specified

Resolution

Single quadrupole analyzer with a pre-filter maximizes resolution and transmission of ions.

Sensitivity

Dual off-axis ion guides provide greater sensitivity by eliminating neutral species.

Speed

30-second analysis
Rapid triage of seized drug materials
Real-time sample analysis

Dynamic Range

Not specified

Mass Range

Not specified

Detection Limit

Not specified

Detector

Low-noise, off-axis, long-life photomultiplier detector.

Ionization Method

Integrated ASAP source (Atmospheric Pressure Sample Analysis Probe).

Ion Source

Pre-optimized ASAP source.

Interface

Not specified

Gas Flow and Requirements

Includes a de-clustering cone gas.

Mass Analyzer

Single quadrupole analyzer with a pre-filter.

Quadrupole

Single quadrupole mass detector.

Chromatography

Designed for direct analysis without the need for separation.

Sample Handling

Samples are loaded directly onto a capillary.

Injection System

Direct sample introduction via the ASAP probe.

Data Acquisition

Allows real-time sample analysis.

Data Analysis

LiveID™ Software enables real-time classification of samples
Spectral library matching

Automation

Automated mass calibration and resolution verification
Automated diagnostics, checks, and alerts

Software

Supported on MassLynx™
Includes LiveID™ and IonLynx software

Ease of Use

Easy access to MS technology
Simple to operate with minimal training

Maintenance and Durability

Long-life photomultiplier detector
Tool-free access to user-serviceable elements

Operating Conditions

Temperature control programmable as isothermal, ballistic ramp, or stepped temperature profile.

Power and Cooling

Power supply: 100–240 V AC, 50/60 Hz.

Dimensions and Footprint

Width: 34.4 cm
Height: 27.1 cm
Depth: 73.0 cm
Weight: 34 kg

Brand and Model

Brand: Waters Corporation
Model: RADIAN ASAP

Documentation and Support

Waters Corporation contact information
Website: waters.com/RADIAN

Compatibility and Connectivity

Supported on MassLynx™
No detailed information available on other connectivity options.

Configuration and Options

Available in Performance and Standard system configurations.

Licensing and Certification

Regulatory approvals: CE, CB, NRTL (CAN/US), RCM.

Cost and Operational Expenses

Designed for low-cost analysis.
Specific cost figures not provided.

PerkinElmer NexION 1100 ICP Mass Spectrometer

Mass Accuracy

Less than 0.05 amu over 8 hours of continuous operation for 7Li, 24Mg, 115In, and 238U.

Resolution

Full-sized Transmission Analyzer Quadrupole provides custom resolution < 0.3 amu², typical operating resolution of < 0.7 amu.

Sensitivity

7Li > 20 Mcps/(mg/L)
115In > 100 Mcps/(mg/L)
238U > 80 Mcps/(mg/L)

Speed

The NexION 1100, with HTS flow injection, reduces sample processing time to 55s for 56 elements while minimizing carryover.

Dynamic Range

10¹⁰ with the option to increase it to 10¹⁴ using the Extended Dynamic Range (EDR) capability.

Mass Range

1 - 285 amu

Detection Limit

9Be ≤ 0.4 ng/L
115In ≤ 0.1 ng/L
209Bi ≤ 0.1 ng/L

Detector

Dual-stage discrete dynode electron multiplier

Ionization Method

Inductively Coupled Plasma (ICP)

Ion Source

Plasma

Interface

Triple Cone Interface (TCI)

Gas Flow and Requirements

• Argon Gas Purity: ≥ 99.996%


• Flow Rate: 12–20 L/min (typical: 15–20 L/min)


• Pressure: 586–690 kPa (85–100 psig)


• Cell Gas Purity: Refer to table below

Mass Analyzer

Quadrupole

Quadrupole

Triple-quad design consisting of:
Quadrupole Ion Deflector (Q0)
Quadrupole Universal Cell (Q1)
Transmission Analyzer Quadrupole (Q2)

Chromatography

Not applicable. The NexION 1100 ICP-MS is not designed for chromatography.

Sample Handling

• All Matrix Solution (AMS) system enables up to 200x online dilution and handles samples with up to 35% total dissolved solids.


• High Throughput System (HTS) ensures fast sample processing with NexION 1100.

Injection System

The NexION 1100 ICP-MS is compatible with a variety of autosamplers.

Data Acquisition

Discrete Dynode Detector allows for rapid data acquisition rates, capturing both analog and pulse signals simultaneously.

Data Analysis

• Quantitative analysis: External calibration, matrix-matched calibrations, standard additions, isotope ratios, isotope dilutions.


• Semi-quantitative analysis.


• FastQuant™ Data Viewer for data review, processing, and export.

Automation

Automated system startup, shutdown, optimization and instrument tuning (including torch alignment) are available through the Syngistix software.

Software

Syngistix™ for ICP-MS Software v.4.0 or higher

Ease of Use

LCD Touchscreen for critical day-to-day tasks including hardware control, results review, instrument parameter diagnostics, analytics, access to embedded training videos and more.
External status LED lighting for easy visibility of the state of analysis.
Syngistix for ICP-MS Software features user-friendly interface and intuitive workflows.

Maintenance and Durability

• LumiCoil™ technology requires no maintenance, replacement, or cooling; guaranteed for instrument lifetime.


• Triple Cone Interface minimizes maintenance; only cone cleaning required.


• Universal Cell designed for long-term use without frequent replacement.

Operating Conditions

Temperature: 15 and 30 °C (59 - 86 °F) optimal, 3 °C (5 °F) rate of change.
Humidity: 20 - 80% (non-condensing)

Power and Cooling

• Power: 16 A max continuous, 50/60 Hz operating frequency.


• Cooling Water: 18 °C supply temperature, 3.8 L/min (min) / 4.7 L/min (typical), 413 ± 14 kPa pressure.


• Optional GreenCT™ Cooling System for energy-efficient cooling.

Dimensions and Footprint

Width: 81 cm (32 in.)
Height: 73 cm (29 in.)
Depth: 72 cm (28 in.)
Weight: 150 kg (330 lb.)

Brand and Model

PerkinElmer NexION® 1100 ICP Mass Spectrometer

Documentation and Support

The sources include various application notes, brochures, case studies, flyers, guides, product notes, regulatory compliance certifications, technical notes, videos, and webinars related to the NexION 1100 ICP-MS.

Compatibility and Connectivity

Compatible with various accessories and peripherals, including autosamplers, high throughput systems, and flow injection modules from PerkinElmer, ESI, and CETAC.

Configuration and Options

Single gas channel can be upgraded to two or three channels for enhanced interference removal capability.
Peltier Cooler (PC3) can be added for analyzing organic solvents.

Licensing and Certification

• CE Mark certified


• Meets EN 61010-1:2010, EN 61010-2-081


• Compliant with European EMC Directive 2014/30/EU


• Fulfills EN 61326-1:2013


• WEEE Directive 2012/19/EU


• RoHS 2.68 compliance

Cost and Operational Expenses

Information not available in the sources.

Shimadzu On-Column Derivatization GC-MS System

Mass Accuracy

±0.1 Da

Resolution

0.1 Da

Sensitivity

10 fg (femtogram)

Speed

Significantly shortened derivatization time due to on-column derivatization.

Dynamic Range

10⁶

Mass Range

1 - 1000 amu

Detection Limit

0.05 ng

Detector

Electron Multiplier (EM)

Ionization Method

Electron Impact (EI)

Ion Source

Standard EI source

Interface

Direct inlet interface

Gas Flow and Requirements

1.5 - 2.0 mL/min (Helium)

Mass Analyzer

Quadrupole

Quadrupole

3-stage quadrupole

Chromatography

Gas Chromatography

Sample Handling

Direct analysis of extracted urine samples without additional pretreatment.

Injection System

Auto-injector AOC-30i with 2-step injection.

Data Acquisition

High-speed data acquisition (10 Hz)

Data Analysis

Shimadzu LabSolutions

Automation

Automatic on-column derivatization using the AOC-30i auto-injector and the 2-step injection feature of the LabSolutions GCMS system.

Software

LabSolutions GCMS (requires specific versions for 2-step injection).
Optionally, GCMSsolution software can be used, but it requires additional software for 2-step injection.

Ease of Use

On-column derivatization simplifies sample preparation and reduces analysis time.

Maintenance and Durability

High durability, low maintenance needs

Operating Conditions

10°C to 40°C (ambient temperature)

Power and Cooling

100 - 240 V, 50/60 Hz, Forced air cooling

Dimensions and Footprint

630 mm (W) x 800 mm (D) x 420 mm (H)

Brand and Model

Analysis of phenethylamine drugs, such as methamphetamine and MDMA, in urine samples.

Documentation and Support

Shimadzu On-Column Derivatization GC-MS System, specifically compatible with GCMS-QP2050 and GCMS NX series.

Compatibility and Connectivity

USB, Ethernet, RS-232

Configuration and Options

Compatible with AOC-20i + 20sU, AOC-30i, and AOC-30i + 20 sU autoinjector and sampler configurations.

Licensing and Certification

CE, UL, RoHS compliant

Cost and Operational Expenses

Varies, typically high initial cost, low operational expenses