Thermofisher Orbitrap Exploris 120 Mass Spectrometer

Mass Accuracy

• External calibration: <3 ppm RMS drift over 24 hours


• Internal lock mass calibration: <1 ppm RMS drift over 24 hours


• EASY-IC: <1 ppm RMS drift for at least 5 days


• <1 ppm mass accuracy levels with a single calibration for full mass range

Resolution

Up to 120,000 at m/z 200145

Sensitivity

Full Scan: < 3.0 fg reserpine on column
tMS2: < 3.0 fg reserpine on column
tSIM: < 1.5 fg reserpine on column

Speed

Up to 22 Hz at resolution setting at 15,000

Dynamic Range

>5000:1 within a single Orbitrap mass analyzer spectrum
>5,000 within a single Orbitrap mass analyzer spectrum

Mass Range

40 to 3000 m/z56
Standard mass range m/z 40–3,000

Detection Limit

< 3.0 fg reserpine on column

Detector

Independent Charge Detector

Ionization Method

Electrospray ionization (ESI)
Heated electrospray ionization (H-ESI)

Ion Source

Thermo Scientific™ OptaMax™ NG ion source

Interface

Atmospheric pressure ionization (API) interface

Gas Flow and Requirements

• Source gas: High-purity nitrogen (>99% pure) at 600 ± 50 kPa (6.0 ± 0.5 bar, 87 ± 7 psi)


• A pre-regulator may be needed to maintain stable source gas pressure


• HCD collision gas: Ultra-high-purity nitrogen (UHP >99.999% pure) at 600 ± 50 kPa (6.0 ± 0.5 bar)


• For EASY-IC: Ultra-high-purity nitrogen (UHP >99.999% pure) at 600 ± 50 kPa (6.0 ± 0.5 bar)

Mass Analyzer

Orbitrap312
High-Field Orbitrap8
Thermo Scientific™ Orbitrap™ mass analyzer

Quadrupole

Advanced quadrupole technology (AQT)

Chromatography

LC-MS

Sample Handling

• Supports flow rates from 1 to 1,000 µL/min for diverse sample introduction methods


• Includes heated electrospray ionization (H-ESI) source for enhanced performance

Injection System

Compatible with various liquid chromatography systems, allowing for flexible and efficient sample injection tailored to specific laboratory workflows.

Data Acquisition

High-speed real-time data acquisition and instrument control

Data Analysis

Thermo Scientific™ Orbitrap Exploris™ instrument control software
Thermo Scientific™ Xcalibur™ software

Automation

Features ready-to-run method templates for various analytes and matrices
Drag-and-drop user interface to accelerate method development, enhancing laboratory automation.

Software

Thermo Scientific™ Orbitrap Exploris™ instrument control software
Thermo Scientific™ Xcalibur™ software

Ease of Use

Single click calibrations
Drag-and-drop method setup
Predefined experiments driven by next-generation software

Maintenance and Durability

Designed for robust performance over hundreds of injections in complex sample matrices
Ensuring long-term durability and minimal maintenance requirements.

Operating Conditions

Operating environment must be 18–27 °C (64–81 °F)
Relative humidity must be 20–80% with no condensation
Designed for indoor use at an altitude of up to 3,000 m (10,000 ft) above sea level

Power and Cooling

• 2× 208–240 Vac single phase, 15 A, 50/60 Hz, with earth ground for instrument and source vacuum pump


• 208–240 Vac single phase, 15 A, 50/60 Hz, with earth ground for the data system


• System averages 3,440 W (11,730 Btu/h) output for air conditioning needs

Dimensions and Footprint

534 × 763 × 703 mm (21 × 30 × 27.7 in)
120 kg (265 lb) without data system, vacuum rough pumps, and optional items

Brand and Model

Thermo Scientific™, Orbitrap Exploris™ 120 mass spectrometer
Orbitrap Exploris 120 MS

Documentation and Support

Comprehensive operating manuals and product specifications are available, providing detailed guidance on system operation and maintenance.

Compatibility and Connectivity

• Seamless integration with Thermo Scientific software platforms: Xcalibur, Chromeleon CDS, and TraceFinder


• Ensures compatibility and connectivity within laboratory workflows

Configuration and Options

APCI/APPI probe for OptaMax NG ion source
Thermo Scientific™ FAIMS Pro Duo interface

Licensing and Certification

For Research Use Only
Not for use in diagnostic procedures

Cost and Operational Expenses

Pricing is available upon request from Thermo Fisher Scientific
A refurbished unit has been listed at $225,000