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PERFORMANCE
Mass Accuracy
Resolution
Sensitivity
Speed
Dynamic Range
MASS RANGE AND ANALYTE DETECTION
Mass Range
Detection Limit
Detector
IONIZATION, SOURCE AND INTERFACE
Ionization Method
Ion Source
Interface
Gas Flow and Requirements
MASS ANALYZER
Mass Analyzer
Quadrupole
CHROMATOGRAPHY AND SAMPLE HANDLING
Chromatography
Sample Handling
Injection System
DATA ACQUISITION AND ANALYSIS
Data Acquisition
Data Analysis
AUTOMATION AND SOFTWARE
Automation
Software
OPERATIONAL FEATURES
Ease of Use
Maintenance and Durability
Operating Conditions
Power and Cooling
Dimensions and Footprint
GENERAL INFORMATION
Brand and Model
Documentation and Support
Compatibility and Connectivity
Configuration and Options
Licensing and Certification
Cost and Operational Expenses
Agilent 6230B Time of Flight (TOF) LC/MS
PERFORMANCE
Mass Accuracy
< 1 ppm RMS (positive)
Resolution
> 22,000 at m/z 1522 independent of acquisition rate
Sensitivity
Low picogram on-column sensitivity
Speed
Up to 44 spectra/second
Dynamic Range
5 orders
MASS RANGE AND ANALYTE DETECTION
Mass Range
m/z 25-20,000
Detection Limit
10 pg/mL (typical)
Detector
TOF (Time of Flight) Detector
IONIZATION, SOURCE AND INTERFACE
Ionization Method
Electrospray Ionization (ESI), APCI
Ion Source
ESI, AJS, APCI, MultiMode (ESI+APCI), NanoESI, CE-ESI
Interface
Capillary electrophoresis, SFC, 2D-LC, and GC-APCI chromatographic interfaces
Gas Flow and Requirements
10–20 L/min (nitrogen)
MASS ANALYZER
Mass Analyzer
Time of Flight (TOF)
Quadrupole
Not applicable, as this is a Time of Flight (TOF) LC/MS system.
CHROMATOGRAPHY AND SAMPLE HANDLING
Chromatography
Liquid Chromatography (LC)
Sample Handling
Autosampler with 96-well plate capacity
Injection System
Dual ESI/APCI interface, manual or automated injection
DATA ACQUISITION AND ANALYSIS
Data Acquisition
MassHunter
Data Analysis
MassHunter
AUTOMATION AND SOFTWARE
Automation
Yes, full automation supported
Software
MassHunter, MassHunter WalkUp, Mass Profiler Professional, MassHunter VistaFlux, MassHunter BioConfirm
OPERATIONAL FEATURES
Ease of Use
One-click SWARM autotune and WalkUp software
Maintenance and Durability
Low-maintenance with periodic calibration; long-lasting parts
Operating Conditions
Temperature: 10–40°C, Humidity: 10–90% RH (non-condensing)
Power and Cooling
100–240V, 50/60 Hz; Air cooling or optional water cooling
Dimensions and Footprint
83.5 x 68.8 x 62.5 cm (W x D x H)
GENERAL INFORMATION
Brand and Model
Agilent, 6230B Time of Flight (TOF) LC/MS56
Documentation and Support
Application Notes, Familiarization Checklists, Installation Guides, Specifications
Compatibility and Connectivity
Compatible with Agilent Bio-inert HPLC systems
Configuration and Options
Choice of ESI, AJS, APCI, MultiMode (ESI+APCI), NanoESI, and CE-ESI ion sources
Licensing and Certification
CE, UL, RoHS compliant
Cost and Operational Expenses
Varies based on configuration, operational costs include consumables, service, and utilities