Liquid Handling Systems

Key Features of Automated Liquid Handling Systems

• Liquid handling instruments offer user-friendly software control, quick and ergonomic tip loading, automatic detection of tips, and adjustable aspiration and dispensing speeds to ensure accurate handling of various liquid types. Its compact build allows it to fit conveniently under a laminar flow hood, while an XL model is available for handling an additional plate.
• The pipettor delivers fast and accurate microplate handling, with a touchscreen interface that allows easy saving and modification of settings like volume, speed, and height. Its compact, open design accommodates SBS-standard labware and external instruments, while functions such as automatic tip sealing, preloaded tip racks, and programmable dispense patterns provide efficient, consistent, and versatile workflows.
• Certain models include a digital display that makes it simple for users to confirm the chosen volume. The volume can be adjusted with ease using a smoothly rotating knob or dial for intuitive operation.
• The systems provide precise liquid dispensing with a flexible volume range to suit diverse experimental requirements. They also enable plate reformatting, allowing sample transfers across formats ranging from single wells to 96-, 384-, and 1536-well plates.
• Automated liquid handling robots employ air-displacement pipetting with a patented lock-and-key mechanism, complemented by optional anti-droplet control and liquid-level detection for precise volume handling from sub-microliters to larger quantities. Their modular architecture supports the integration of cameras, tube transport, and diverse tools, enabling adaptable deck layouts that can hold multiple microplates or tube positions across pipetting channels.
• Multichannel pipettes feature a universal-fit tip nozzle, ensuring compatibility with a wide variety of pipette tips and enhancing workflow flexibility. They are equipped with an ergonomically designed tip ejector lever that enables smooth and effortless tip removal. This design minimizes strain during use, supporting comfort over extended periods. As a result, they maintain consistent performance even during long laboratory sessions.

Applications of Automated Liquid Handlers

• ELISA and immunoassays: Multichannel liquid equipment simplifies the addition of reagents and transfer of samples into microplates, minimizing well-to-well variability and ensuring consistent, efficient results in high-throughput immunoassays.
• Drug discovery: In drug discovery, automated systems enable high-throughput screening, letting researchers quickly evaluate thousands of compounds and efficiently pinpoint potential candidates.
• Cell culture: The systems assist with media preparation, cell seeding, and the precise addition of growth factors or drugs. Their versatility ensures accurate handling of varying liquid volumes across different experiments.
• Environmental & food testing: The systems are used for processing samples in contaminant detection, microbial analysis, and food quality assessments. Their ability to accurately transfer different sample volumes enhances the reliability of test results.
• Analytical chemistry: Variable volume pipetting systems are essential for preparing samples for techniques such as HPLC, GC, and mass spectrometry. Their precise dispensing ensures uniform sample quality and reproducible analytical outcomes.
• Flow cytometry: Liquid handlers efficiently prepare and stain cells for flow cytometry, ensuring uniform sample processing and minimizing variability between experiments.
• Nucleic acid extraction: Liquid handlers automate the isolation of DNA or RNA from different sample types, which boosts throughput while preserving sample integrity and consistency.
• Primary sample reformatting: Robotic systems streamline the transfer of primary samples into multi-well plates for further analysis, saving time and minimizing the risk of cross-contamination.
• Miniaturized screenings: Automation allows high-throughput testing in compact formats, like 384- or 1536-well plates, saves reagents, and ensures precise and reproducible results.
• Whole blood fractionation: Liquid handlers facilitate the separation of plasma, serum, and cellular components from whole blood, standardizing sample processing and minimizing variability.
• ADME-Tox studies: Multichannel pipettes enable the preparation of multiple replicates across plates for pharmacokinetic and toxicity assays and enhance the reliability and consistency of the results.

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