Bruker CaptiveSpray Ion Source

CaptiveSpray Ion Source enhances sensitivity, reproducibility, and ease of use for high-throughput mass spectrometry applications.

STARTING PRICE

$30,000.00

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Features

  • Optimized for exceptional sensitivity and reproducibility
  • Easy-to-use design for seamless integration
  • Compatible with Bruker mass spectrometers
  • Suitable for high-throughput analysis and complex sample types

Applications

  • Proteomics and metabolomics studies
  • Drug discovery and development
  • Environmental analysis
  • Food and beverage testing
Bruker CaptiveSpray Ion Source

Product Specifications

PERFORMANCE

Mass Accuracy
<1 Da (depends on the instrument)
Resolution
Up to 100,000 (depends on instrument)
Sensitivity

  • High Sensitivity: Essential for deep proteome analysis, especially with CaptiveSpray Ultra 2.

  • Optimized Performance: Enhanced by a clean nebulizer gas supply.

Speed
Fast (ms-level)
Dynamic Range
10^4 - 10^6

MASS RANGE AND ANALYTE DETECTION

Mass Range
50 Da to > 5000 Da
Detection Limit
Low fmol level (depends on sample)
Detector
ESI/MSD (Electrospray Ionization Mass Spectrometer)

IONIZATION, SOURCE AND INTERFACE

Ionization Method
Electrospray Ionization (ESI), implied by the context of nanoflow rates and use with LC
Ion Source
CaptiveSpray 2
CaptiveSpray Ultra
Interface
Ionization source (CaptiveSpray)
Gas Flow and Requirements
Nebulizing gas flow is used, but specific requirements are not provided

MASS ANALYZER

Mass Analyzer
Typically quadrupole or TOF (Time of Flight)
Quadrupole
Optional in some configurations

CHROMATOGRAPHY AND SAMPLE HANDLING

Chromatography
Liquid Chromatography (LC), specifically mentioned in relation to gradients and nano-flow rates
Sample Handling
Liquid sample introduction
Injection System
Direct infusion or via autosampler

DATA ACQUISITION AND ANALYSIS

Data Acquisition
High-speed data acquisition
Data Analysis
Post-acquisition analysis (software)

AUTOMATION AND SOFTWARE

Automation
Fully automated (with software)
Software
Bruker software (e.g., Compass)

OPERATIONAL FEATURES

Ease of Use

  • Simplified Installation: "On-off" design for quick setup.

  • Easy Maintenance: Front-accessible design enables fast emitter changes.

  • Precision Alignment: Zero-adjustment sprayer positioning ensures optimal performance.

Maintenance and Durability
Tool-less installation and maintenance
Integrated air filter for clean nebulizer gas
Operating Conditions
Atmospheric pressure (for ESI)
Power and Cooling
Requires stable electrical supply
Water cooling (for some models)
Dimensions and Footprint
Typically small, varies with model

GENERAL INFORMATION

Brand and Model
Bruker CaptiveSpray 2
Bruker CaptiveSpray Ultra 2
Documentation and Support
Assumed to be available from Bruker, but not specified in the source
Compatibility and Connectivity

  • Broad Column Compatibility: Supports all PepSep™ columns, IonOpticks Aurora Series CSI Range, and custom self-made columns.

  • Optimized for timsTOF: Specifically designed for timsTOF systems.

  • Integrated Heating: Column oven attached to the source for precise temperature control.

Configuration and Options
Choice of two CaptiveSpray 2 Emitters (10 µm and 20 µm ID)
Licensing and Certification
For Research Use Only. Not for use in clinical diagnostic procedures
Cost and Operational Expenses
Medium-high operational cost (depends on setup and usage)

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