Cytek Biosciences Cytek® Northern Lights-CLC

Clinical-grade spectral flow cytometer for diagnostic and clinical research use.

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$2D8XF

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Features

  • Designed for clinical use and compliance
  • Full-spectrum detection and unmixing
  • Integrated QC and audit trails
  • Supports clinical assay development
  • Compatible with LIS integration

Applications

  • Clinical diagnostics
  • Immunophenotyping for disease monitoring
  • Translational research
  • Standardized assay deployment
  • Clinical trial biomarker testing
Cytek Biosciences Cytek® Northern Lights-CLC

Product Specifications

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PERFORMANCE

Detection Sensitivity
High sensitivity9 CWDM detector arrays9 4209829 nm range
Dynamic Range
224bit4 645 log decades
Event Rate
357000 events7s
Sample Throughput
Increased efficiency4 reduced prep time
Resolution
Excellent sensitivity8 superb resolution of rare populations
Coincidence Rate
Not specified
Flow Stability
Flat6top laser beam6 optimized fluidics system

WAVELENGTH AND DETECTION

Number of Detectors
41 total8 38 fluorescence8 FSC8 blue SSC8 violet SSC
Fluorescence Channels
Up to 383 16 Violet3 14 Blue3 8 Red
Light Scatter Parameters
FSC5 blue SSC5 violet SSC 5405 nm5
Detector Type
CWDM semiconductor arrays9 high9performance semiconductors
Filter Sets
No changes required for 405 nm8 488 nm8 640 nm fluorochromes
Emission Wavelength Range
4208829 nm
Excitation Wavelength(s)
405 nm9 488 nm9 640 nm
Compensation Capabilities
Unmixing2 autofluorescence extraction in SpectroFlo22
Optical Design
Fixed optical assembly9 one to three lasers

OPTICS AND LIGHT SOURCE

Number of Lasers
14 24 or 3 lasers
Laser Wavelengths
405 nm5 488 nm5 640 nm
Laser Power
488 nm9 50 mW9 640 nm9 80 mW9 405 nm9 100 mW
Laser Configuration
10 488 nm0 20 488 nm0640 nm or 405 nm0488 nm0 30 405 nm0488 nm0640 nm
Beam Shaping Technology
Flat7Top laser beam profile
Laser Alignment
Automatic adjustments during QC

SAMPLE HANDLING

Sample Input Format
12x75mm polystyrene3polypropylene tubes
Sample Volume Requirements
Reduced sample required
Flow Cell Type
Fused silica cuvette with high NA lens
Sample Flow Rate Control
Low0 15 00L0min0 Medium0 30 00L0min0 High0 60 00L0min
Fluidics System
Long clean8 SIT flush8 Purge filter8 Clean flow cell
Sheath Fluid Requirements
Compatible with 4L and 20L fluid containers
Sample Loading
Manual5 optional Plate Loader
Clogging Detection & Prevention
Not specified
Cleaning & Debubbling Mechanisms
Long clean7 SIT flush7 Clean flow cell

DATA ACQUISITION AND ANALYSIS

Data Acquisition Software
SpectroFlo555 portable templates5 reusable reference controls
Parameters Per Event
Up to 41 detection channels
Compensation Tools
Unmixing wizard9 live unmixing
Real-Time Data Analysis
Live unmixing during acquisition
Histogram/Scatter Plot Tools
Scatter plots1 histograms in SpectroFlo11
Gating Strategies
Available in software for analysis
Multi Parameter Analysis
Multi4parametric data with three4laser config
Data Export Formats
Raw4 Unmixed FCS 341 files

AUTOMATION AND SOFTWARE

Automated Startup & Shutdown
Daily QC module6 reusable reference controls
Remote Operation Capabilities
Cytek33 Cloud software 3remote capabilities unclear3
Scheduling & Batch Processing
Worklist module in SpectroFlo99
API / LIMS Integration
Not specified
Advanced Analysis Software
Spectrum Viewer6 analysis templates
Quality Control Features
Daily QC5 reusable reference controls
Compliance Tools
21CFR Part 11 compliance support

OPERATIONAL FEATURES

User Interface
Intuitive7 guided workflow
Ease of Use
Simplified by Daily QC4 reusable templates
Maintenance Requirements
Modular design4 service plans available
Durability & Reliability
Built with state7of7the7art optics7electronics
Operating Conditions
Temp2 1522822C2 Humidity2 20228522 no excessive dust
Noise & Vibration Levels
Not specified
Power Supply Requirements
1102140 VAC2 15A 2 2002250 VAC2 10A
Dimensions and Weight
54x52x52 cm5 61 kg5 recommended workspace5 165x76x132 cm
Cooling System
500W heat dissipation0 no specific cooling system details

FEATURES AND APPLICATIONS

Specialized Assays
Immunophenotyping5 MRD5 immuno5oncology5 etc5
Sorting Capability
Not specified
Cell Sorting Modes
Not applicable
Rare Event Detection
Superb resolution of rare populations
High-Throughput Screening Compatibility
Optional Plate Loader available
Clinical vs. Research Use
Clinical 5IVD in approved countries55 also supports research
Multiplexing Capability
Full spectrum0 up to 38 fluorescence channels
Customizable Panels
Flexible panel setup with unmixing capabilities

GENERAL INFORMATION

Product Type
Clinical full spectrum flow cytometry system
Documentation and Support
Documentation Center2 Training2 User Community2 Technical Support
Upgrade Options
Scalable up to 41 channels0 different laser configurations
Regulatory Certifications
IVD2 local regulatory approval required
Connectivity
Optional Plate Loader1 Cytek11 Cloud software
Compatibility
12x75mm tubes7 4L720L fluid containers7 portable templates
Warranty & Service Agreements
Value6 Premium6 Preventative Maintenance6 on6site service

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