Shimadzu LCMS-2050 Single Quadrupole LC-MS

Shimadzu LCMS-2050

Shimadzu LCMS-2050: High-performance single quadrupole LC-MS for fast, sensitive, and reliable qualitative & quantitative analysis.

STARTING PRICE

$200,000.00

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Features

High sensitivity with reduced noise
Ultra-fast data acquisition
Advanced ionization capabilities
User-friendly interface
Compact design for space efficiency
Suitable for various applications in pharmaceutical, environmental, and food industries

Applications

Pharmaceutical analysis
Environmental testing
Food safety and quality control
Forensic analysis
Clinical research and diagnostics

Product Specifications

PERFORMANCE

Mass Accuracy

Using the deconvolution function of LabSolutions™ LCMS, the molecular weight of nusinersen is estimated to be 7127.18 at an accuracy of 0.05 Da error to the theoretical value (7127.23).

Resolution

0.1 Da (unit resolution)

Sensitivity

High speed, sensitivity, and wide mass range.

MS detectors offer greater sensitivity than optical detectors.

Heated DUIS source enhances detection of diverse compounds.

Reliable quantitation at ultra-low concentrations.

Supports qualitative and quantitative sugar analysis.

Speed

Analyzes a wide range of compounds from high to low polarity.

Compact design with high speed and sensitivity.

Industry-leading scan speed and fast polarity switching.

Detects positive and negative ions at 15,000 u/sec scan speed.

Optimized for UHPLC to capture sharp peaks accurately.

Dynamic Range

10^7 (linear dynamic range)

MASS RANGE AND ANALYTE DETECTION

Mass Range

The wide mass range of the LCMS-2050 is a powerful tool for molecular weight determination of large molecules such as oligonucleotides, peptides, proteins, polymers, and more.

Detection Limit

1 fg (femtogram) for typical compounds

Detector

Photomultiplier Tube (PMT)

IONIZATION, SOURCE AND INTERFACE

Ionization Method

Equipped with the newly developed Heated Dual Ion Source (Heated DUIS™).

Combines electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI).

Offers the benefits of two widely used mass spectrometry techniques.

Ion Source

Heated DUIS™

Interface

Atmospheric Pressure Ionization (API)

Gas Flow and Requirements

Dry gas: 10 L/min, Nebulizing gas: 3 L/min, CDL gas: 3 L/min

MASS ANALYZER

Mass Analyzer

The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy-to-use high-level performance and compactness.

Quadrupole

Single quadrupole

CHROMATOGRAPHY AND SAMPLE HANDLING

Chromatography

Seamless integration with LC by design.

Compatible with Shimadzu LC systems, including analytical, preparative, and legacy models.

Supports high-performance liquid chromatography (HPLC) for compound analysis.

Sample Handling

Auto-sampler available

Injection System

Split/splitless injection, Continuous Flow Controller (CFC)

DATA ACQUISITION AND ANALYSIS

Data Acquisition

The vacuum system is ready in as little as 6 minutes, enabling rapid mass data acquisition after a power interruption.

Data Analysis

Equipped with Analytical Intelligence for advanced data analysis.

Eco-conscious functions reduce labor and energy consumption.

Mass-it displays mass information for quick data interpretation.

LabSolutions LCMS workstation enables streamlined instrument control and analysis.

AUTOMATION AND SOFTWARE

Automation

Yes, with optional auto-sampler and software integration.

Software

LabSolutions™ LCMS, Open Solution (optional open access software).

OPERATIONAL FEATURES

Ease of Use

The system is enhanced with technology and functions to ensure that even technicians unfamiliar with mass spectrometers can easily and efficiently perform analysis.

The LCMS-2050 provides high speed, high sensitivity, and a wide mass range that are the hallmarks of Shimadzu mass spectrometers.

The system can be accessed as if it were an LC that you simply turn ON and use.

Maintenance and Durability

The ionization interface of the LCMS-2050 has a simple, accessible design that minimizes the efforts needed to maintain the instrument in a good state.

Quick and easy maintenance means less downtime, labor, and cost.

Operating Conditions

Temperature: 4-40°C, Relative Humidity: 30-85% RH

Power and Cooling

The LCMS-2050 achieves energy savings of 43% in comparison with the LCMS-2020.

Dimensions and Footprint

540 mm

GENERAL INFORMATION

Brand and Model

Shimadzu LCMS-2050

Documentation and Support

The LabSolutions LCMS workstation is equipped with an advanced Help function and an extensive FAQ section to support an in-depth understanding of LCMS analysis.

Compatibility and Connectivity

Seamless Connectivity with Shimadzu LC Systems.

The LCMS-2050 can be integrated into any Shimadzu LC architecture whether it is a high throughput analytical system, a preparative LC with fraction collection, or even a legacy model.

Configuration and Options

Optional front-end ion source, various sampling systems.

Licensing and Certification

For Research Use Only. Not for use in diagnostic procedures.

Cost and Operational Expenses

The LCMS-2050 contributes to significant energy savings and improved operational efficiency.