Shimadzu LCMS-8050
Shimadzu LCMS-8050: High-sensitivity, high-speed LC-MS system for precise qualitative and quantitative analysis.
Features
- High sensitivity for trace analysis
- Fast and reliable quantitative and qualitative results
- Robust and easy to maintain
- UF-switching and UF-scanning technologies
Applications
- Environmental analysis
- Pharmaceutical research
- Clinical diagnostics
- Food safety testing
Product Specifications
PERFORMANCE
Mass Accuracy
Maintains mass accuracy, even at the highest scan speed of 30,000 u/sec1
Resolution
< 0.5 Da
Sensitivity
30 times that of the LCMS-8030.
High sensitivity is achieved through the use of a newly designed heated ESI probe and a high-efficiency CID cell, the UFsweeper™ III3.
Excellent reproducibility even at attogram (ag) levels
High sensitivity is achieved through the use of a newly designed heated ESI probe and a high-efficiency CID cell, the UFsweeper™ III3.
Excellent reproducibility even at attogram (ag) levels
Speed
High-speed (+/-) ionization switching in 5 msec.
High-speed scanning at 30,000 u/sec6.
High-speed MRM at 555 MRM/sec
High-speed scanning at 30,000 u/sec6.
High-speed MRM at 555 MRM/sec
Dynamic Range
Enhanced dynamic range compared to other triple quadrupoles8.
MASS RANGE AND ANALYTE DETECTION
Mass Range
10 Da to 2,000 Da
Detection Limit
Achieved LOQs that fulfill the 1/100 target value without sample pre-concentration
Detector
Ultrafast response detector allows high-speed positive/negative ion mode switching of the detector voltage
IONIZATION, SOURCE AND INTERFACE
Ionization Method
Electrospray ionization (ESI) is used, specifically with a heated ESI probe
Ion Source
Heated ESI probe3.
The heated ESI probe combines a high-temperature gas with the nebulizer spray to improve desolvation efficiency
The heated ESI probe combines a high-temperature gas with the nebulizer spray to improve desolvation efficiency
Interface
Electrospray Ionization (ESI), Atmospheric Pressure Chemical Ionization (APCI)
Gas Flow and Requirements
Heating gas flow and nebulizer gas flow
MASS ANALYZER
Mass Analyzer
Triple quadrupole mass spectrometer
Quadrupole
Qarray™ ion guide effectively focuses ions over a wide m/z range.
High-performance hyperbolic mass filter with a proven track record in LC/MS
High-performance hyperbolic mass filter with a proven track record in LC/MS
CHROMATOGRAPHY AND SAMPLE HANDLING
Chromatography
Compatible with Nexera UHPLC
Sample Handling
Autosampler, Direct Injection, Solid Phase Extraction
Injection System
Shimadzu AOC-20i Autosampler, Syringe Injection
DATA ACQUISITION AND ANALYSIS
Data Acquisition
The LCMS-8050 is capable of simultaneously acquiring MRM transitions per second without sacrificing accuracy and precision.
A high sampling rate delivers precise and accurate quantitation for quantitation ions, reference ions, and internal standard ions even in chromatographic regions with unresolved peaks
A high sampling rate delivers precise and accurate quantitation for quantitation ions, reference ions, and internal standard ions even in chromatographic regions with unresolved peaks
Data Analysis
LabSolutions Connect™ / LabSolutions Insight™
AUTOMATION AND SOFTWARE
Automation
MRM and ion source parameters are automatically optimized
Software
LabSolutions Connect™ and LabSolutions Insight™
OPERATIONAL FEATURES
Ease of Use
Easy system maintenance reduces downtime.
Replacing the desolvation line (DL) and ESI capillary is quick and easy.
The DL can be replaced without breaking vacuum.
Newly designed ionization unit can be removed simply by releasing a one-touch lever
Replacing the desolvation line (DL) and ESI capillary is quick and easy.
The DL can be replaced without breaking vacuum.
Newly designed ionization unit can be removed simply by releasing a one-touch lever
Maintenance and Durability
Maintains high sensitivity even during successive demanding analyses10.
Robustness is achieved through the system's design
Robustness is achieved through the system's design
Operating Conditions
Temperature: 4°C - 40°C, Humidity: 10% - 90% RH
Power and Cooling
100-240 V, 50/60 Hz, Internal Air Cooling
Dimensions and Footprint
77 x 51 x 55 cm (W x D x H), 80 kg
GENERAL INFORMATION
Brand and Model
Shimadzu LCMS-8050, Shimadzu Nexera UHPLC
Documentation and Support
Shimadzu Support, Product Manuals, Application Notes, Service Contracts
Compatibility and Connectivity
USB, Ethernet, Windows PC Compatibility
Configuration and Options
Various ion source options, Multiple detector options
Licensing and Certification
CE, UL, RoHS, ISO certified
Cost and Operational Expenses
Price: ~$150,000.
Annual Maintenance: ~$10,000.
Consumables: Variable
Annual Maintenance: ~$10,000.
Consumables: Variable
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