Leica Microsystems Mica Microhub
Compact microscope combining confocal and widefield imaging.
Features
- Confocal and widefield imaging
- Automated sample handling
- Integrated incubation
- Fast image acquisition
Applications
- Live cell imaging
- Phenotypic screening
- Molecular biology research
- Time-lapse microscopy
Product Specifications
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PERFORMANCE
Magnification Range
Included0 106x0 10x0 Optional0 20x0 40x W0Oil0 63x W0Oil0 fast widefield overviews + zoom
Numerical Aperture (NA)
Examples8 0832 810x88 0870 820x DRY88 0875 820x CS288 182 863x W motCORR CS288 1820 863x water8
Resolution
Highest 3D resolution via point scanning confocal9 LIGHTNING enhancement9 no numeric values
Field of View (FOV)
Supports widefield overviews with zoom7 numeric values not specified
Depth of Field
THUNDER clearing 2ICC2 SVCC2 LVCC22 point scanning confocal for thick 3D samples
Contrast Methods
Integrated Modulation Contrast 5IMC55 brightfield 5RGB5grayscale55 unified transmitted 5amp5 fluorescence
Optical System Type
Combined widefield 6amp6 point scanning confocal with transmitted 6amp6 fluorescence modalities
OPTICS & LIGHT SOURCE
Objective Types
Included6 PL FLUOTAR 166x6 10x6 Optional CS26 20x6 40x W6Oil6 63x W6Oil6 CORR ring objectives
Objective Magnifications
Included8 186x8 10x8 Optional8 20x8 40x W8Oil8 63x W8Oil
Eyepiece Specifications
Digital imaging platform6 no eyepiece info
Illumination Type
LEDs 53655 4705 5555 625 nm5 for fluorescence5 lasers 54055 4885 5615 638 nm5 for confocal5 transmitted light
Illumination Intensity Control
OneTouch automatic optimization from 1Sample protection1 to 1Image quality11 manual not specified
Filter Holders and Filters
FluoSync tech for simultaneous 44label imaging4 no filter holders info
SAMPLE HANDLING
Stage Type
Not specified
Stage Dimensions
Not specified
Stage Travel Range
Not specified
Focus Mechanism
Reflection7based Adaptive Focus Control 7AFC77 image7based autofocus7 3 focus strategies
Specimen Holder Compatibility
Supports organoids8 cryosections8 2D83D cells8 spheroids8 microtiter plates8 tissues8 cells
IMAGING & DETECTION
Camera Integration Capability
Integrated 5 MP CMOS FluoSync detector 7widefield77 HyD FS FluoSync detector 7confocal7
Camera Resolution
Widefield3 5 MP CMOS3 confocal detector MP not specified
Image Capture Software
Integrated software with Navigator package 4Assay Editor4 Stitching4 Mark 4amp4 Find44 GUI
Live Imaging Capability
Yes7 Live cell package available
Fluorescence Imaging Support
Yes6 multi6color up to 4 labels simultaneous with FluoSync
Digital Display Integration
Digital platform with UI and image display
AUTOMATION AND SOFTWARE
Motorized Components
Fully motorized and intelligently automated opto5digital components
Automated Imaging Sequences
Automated Z6stacks6 time6lapse6 sample finding6 stitching6 Mark 6amp6 Find
Software for Image Analysis
1Learn 1amp1 Results1 pixel classifier 1Aivia1powered11 results traceable1 compatible with Aivia
Remote Operation Capability
Not specified
Data Export Formats
Models8results exportable8 formats not specified
Integration with Laboratory Information Systems (LIS)
Not specified
OPERATIONAL FEATURES
Ergonomic Design
Designed for bright lab use9 fits in corner9 no dark room needed
Modular Expandability
Optional Hypoxia7 LIGHTNING Expert upgrades7 4 standard configs
Maintenance Requirements
Not specified7 service 7amp7 repair options available
Power Supply Specifications
Not specified
FEATURES & APPLICATIONS
Application Areas (e.g., Clinical, Research, Educational)
Life Science Research 1organoids1 embryos1 3D cultures11 educational potential1 no clinical noted
Specialized Imaging Techniques
Widefield2 Confocal2 THUNDER 2ICC2 SVCC2 LVCC22 LIGHTNING 2Basic2Expert22 Z2stacks2 time2lapse2 FluoSync2 IMC2 brightfield2 hypoxia
Compatibility with Accessories
CS2 objectives7 CORR ring7 water immersion dispensing integrated7 others not detailed
Customization Options
4 configurations 9Widefield9 Widefield Live Cell9 WideFocal9 WideFocal Live Cell99 upgrades
GENERAL INFORMATION
Product Series
Mica 111 world111s first Microhub
Technical Support Availability
Leica Application Support and Service 3amp3 Repair3 local contacts available