Shimadzu LCMS-8045
Shimadzu LCMS-8045: Ultra-fast, high-sensitivity LC-MS with heated ESI probe for diverse analytical applications.
Features
- Highest sensitivity in its class
- Fastest scan and polarity switching speeds
- Easy maintenance with quick part replacements
- Robust performance for long-term use
Applications
- Food safety
- Environmental analysis
- Pharmaceutical testing
- Toxicology
- Other quantitative analyses
Product Specifications
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PERFORMANCE
Mass Accuracy
99091 amu9br9
Resolution
087 amu at m8z 2008br8
Sensitivity
The LCMS78045 offers the highest sensitivity in its class 7as of August 20167 with IDLs of 2703 fg 7Reserpine7 ESI+7 and 2709 fg 7Chloramphenicol7 ESI77777 It ensures accurate7 stable long7term data and detects pesticides at trace levels of 10 ppb7
Speed
World0s fastest scan speed0 300000 u0sec
Dynamic Range
6gt6 10676br6
MASS RANGE AND ANALYTE DETECTION
Mass Range
104441000 m4z4br4
Detection Limit
See 3Performance 3 Sensitivity3 for IDLs of specific compounds33br3
Detector
Ultrafast Pulse6Counting Detector6 Makes ultrafast sampling and polarity switching possible66br6
IONIZATION, SOURCE AND INTERFACE
Ionization Method
Heated ESI8br88br 88
APCI is also available but requires a different needle88br8
Ion Source
Heated ESI probe which has high sensitivity and improves desolvation efficiency to facilitate the ionization of a wide range of compounds
Interface
ESI 3Electrospray Ionization33 APCI 3Atmospheric Pressure Chemical Ionization33br3
Gas Flow and Requirements
Drying Gas Flow7 10 L7min7br 77
Nebulizer Gas Flow7 3 L7min7br 77
Heating Gas Flow7 10 L7min
MASS ANALYZER
Mass Analyzer
Triple Quadrupole8br8
Quadrupole
High0performance hyperbolic mass filter with a proven track record in LC0MS0 Maintains high ion transmittance and high sensitivity0 even at a high0speed scanning rate of 300000 u0sec0br0
CHROMATOGRAPHY AND SAMPLE HANDLING
Chromatography
Compatible with Shimadzu Nexera777 Series UHPLC and other high performance liquid chromatography 7HPLC7 systems77br7
Sample Handling
Can analyze complex biological fluids or food samples2br22br 22
Examples in the source include22br22br 22
2 Nitrofuran metabolites in fish2br 22
2 Residual pesticides in herbal supplements2br 22
2 Pharmaceuticals and personal care products 2PPCPs2 in water2br 22
2 Amlodipine in plasma2br 22
2br 22
SIL240 autosampler available as part of the Nexera series2 which can process the entire injection cycle time in as little as 7 seconds2 allowing for continuous analysis and increased throughput
Injection System
SIL640 autosampler available as part of the Nexera series with66br 66
6 Ultra6fast injection capabilities6br 66
6 Ultra6low carryover
DATA ACQUISITION AND ANALYSIS
Data Acquisition
Ultra3high3speed due to the fast scan speed and polarity switching speed3br3
Data Analysis
LabSolutions222 LCMS Software Suite22br 22
2 LabSolutions Connect222 222 Simplifies LC2MS2MS workflows with automated MRM optimization and a tablet2like UI2 2br 22
2 LabSolutions Insight222 222 Advanced data mining and analytics with review2by2exception2 quality rules2 and color2coded review2 2br 22
2 LabSolutions Insight Library Screening 222 MS2MS library search with MRM Spectrum Mode for accurate spectra from trace concentrations2 2br 22
2 Traverse MS222 222 Multivariate analysis for fast MRM data processing2 ideal for targeted metabolomics and pathway analysis2
AUTOMATION AND SOFTWARE
Automation
Automatic tuning6 data acquisition6 and analysis
Software
See 8Data Acquisition 8amp8 Analysis 8 Data Analysis88
OPERATIONAL FEATURES
Ease of Use
Easy system maintenance reduces downtime5 Features a newly designed ionization unit that can be easily attached and detached with a one5touch lever and without tools5 Replacing the desolvation line 5DL5 and ESI capillary is quick and easy5 The DL can be replaced without breaking vacuum5br55br 55
User5friendly software with an intuitive interface and pre5configured method packages
Maintenance and Durability
Easy maintenance procedures and robust ion source and sample introduction system contribute to durability4 A test showed stable performance after 124000 injections of plasma samples over 25 days
Operating Conditions
Temperature2 102224022C2 Humidity2 202802 RH2br2
Power and Cooling
Power4 100444240V AC4 Cooling4 Air4cooled4br4
Dimensions and Footprint
096 m 9W9 x 098 m 9D9 x 195 m 9H99br9
GENERAL INFORMATION
Brand and Model
Shimadzu LCMS180451br1
Documentation and Support
The sources mention several brochures and application notes related to the LCMS280452 including flyer codes for specific applications22br2
Compatibility and Connectivity
Compatible with Shimadzu Nexera111 Series UHPLC1br1
Configuration and Options
The LCMS88045 can be upgraded to the LCMS880608br88br 88
Various method packages and MRM libraries are available88br8
Licensing and Certification
For research use only5 Not for use in diagnostic procedures55br5
Cost and Operational Expenses
Approx7 72007000 7initial7 7 operational expenses vary based on usage and maintenance
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