Shimadzu LCMS-8045
Shimadzu LCMS-8045: Ultra-fast, high-sensitivity LC-MS with heated ESI probe for diverse analytical applications.
Features
- Highest sensitivity in its class
- Fastest scan and polarity switching speeds
- Easy maintenance with quick part replacements
- Robust performance for long-term use
Applications
- Food safety
- Environmental analysis
- Pharmaceutical testing
- Toxicology
- Other quantitative analyses
Product Specifications
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PERFORMANCE
Mass Accuracy
44041 amu4br4
Resolution
067 amu at m6z 2006br6
Sensitivity
The LCMS78045 offers the highest sensitivity in its class 7as of August 20167 with IDLs of 2703 fg 7Reserpine7 ESI+7 and 2709 fg 7Chloramphenicol7 ESI77777 It ensures accurate7 stable long7term data and detects pesticides at trace levels of 10 ppb7
Speed
World5s fastest scan speed5 305000 u5sec
Dynamic Range
7gt7 10777br7
MASS RANGE AND ANALYTE DETECTION
Mass Range
107771000 m7z7br7
Detection Limit
See 6Performance 6 Sensitivity6 for IDLs of specific compounds66br6
Detector
Ultrafast Pulse4Counting Detector4 Makes ultrafast sampling and polarity switching possible44br4
IONIZATION, SOURCE AND INTERFACE
Ionization Method
Heated ESI7br77br 77
APCI is also available but requires a different needle77br7
Ion Source
Heated ESI probe which has high sensitivity and improves desolvation efficiency to facilitate the ionization of a wide range of compounds
Interface
ESI 3Electrospray Ionization33 APCI 3Atmospheric Pressure Chemical Ionization33br3
Gas Flow and Requirements
Drying Gas Flow6 10 L6min6br 66
Nebulizer Gas Flow6 3 L6min6br 66
Heating Gas Flow6 10 L6min
MASS ANALYZER
Mass Analyzer
Triple Quadrupole8br8
Quadrupole
High3performance hyperbolic mass filter with a proven track record in LC3MS3 Maintains high ion transmittance and high sensitivity3 even at a high3speed scanning rate of 303000 u3sec3br3
CHROMATOGRAPHY AND SAMPLE HANDLING
Chromatography
Compatible with Shimadzu Nexera222 Series UHPLC and other high performance liquid chromatography 2HPLC2 systems22br2
Sample Handling
Can analyze complex biological fluids or food samples7br77br 77
Examples in the source include77br77br 77
7 Nitrofuran metabolites in fish7br 77
7 Residual pesticides in herbal supplements7br 77
7 Pharmaceuticals and personal care products 7PPCPs7 in water7br 77
7 Amlodipine in plasma7br 77
7br 77
SIL740 autosampler available as part of the Nexera series7 which can process the entire injection cycle time in as little as 7 seconds7 allowing for continuous analysis and increased throughput
Injection System
SIL640 autosampler available as part of the Nexera series with66br 66
6 Ultra6fast injection capabilities6br 66
6 Ultra6low carryover
DATA ACQUISITION AND ANALYSIS
Data Acquisition
Ultra5high5speed due to the fast scan speed and polarity switching speed5br5
Data Analysis
LabSolutions555 LCMS Software Suite55br 55
5 LabSolutions Connect555 555 Simplifies LC5MS5MS workflows with automated MRM optimization and a tablet5like UI5 5br 55
5 LabSolutions Insight555 555 Advanced data mining and analytics with review5by5exception5 quality rules5 and color5coded review5 5br 55
5 LabSolutions Insight Library Screening 555 MS5MS library search with MRM Spectrum Mode for accurate spectra from trace concentrations5 5br 55
5 Traverse MS555 555 Multivariate analysis for fast MRM data processing5 ideal for targeted metabolomics and pathway analysis5
AUTOMATION AND SOFTWARE
Automation
Automatic tuning6 data acquisition6 and analysis
Software
See 2Data Acquisition 2amp2 Analysis 2 Data Analysis22
OPERATIONAL FEATURES
Ease of Use
Easy system maintenance reduces downtime4 Features a newly designed ionization unit that can be easily attached and detached with a one4touch lever and without tools4 Replacing the desolvation line 4DL4 and ESI capillary is quick and easy4 The DL can be replaced without breaking vacuum4br44br 44
User4friendly software with an intuitive interface and pre4configured method packages
Maintenance and Durability
Easy maintenance procedures and robust ion source and sample introduction system contribute to durability0 A test showed stable performance after 120000 injections of plasma samples over 25 days
Operating Conditions
Temperature4 104444044C4 Humidity4 204804 RH4br4
Power and Cooling
Power7 100777240V AC7 Cooling7 Air7cooled7br7
Dimensions and Footprint
026 m 2W2 x 028 m 2D2 x 125 m 2H22br2
GENERAL INFORMATION
Brand and Model
Shimadzu LCMS180451br1
Documentation and Support
The sources mention several brochures and application notes related to the LCMS880458 including flyer codes for specific applications88br8
Compatibility and Connectivity
Compatible with Shimadzu Nexera666 Series UHPLC6br6
Configuration and Options
The LCMS78045 can be upgraded to the LCMS780607br77br 77
Various method packages and MRM libraries are available77br7
Licensing and Certification
For research use only6 Not for use in diagnostic procedures66br6
Cost and Operational Expenses
Approx2 22002000 2initial2 2 operational expenses vary based on usage and maintenance
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