Thermofisher Orbitrap Exploris 120 Mass Spectrometer
Thermo Fisher Orbitrap Exploris 120: High-resolution, sensitive mass spectrometer for fast, precise identification and quantification.
Features
- High-resolution analysis for precise molecular identification
- Advanced ion optics for optimal ion transmission
- Versatile for both qualitative and quantitative analysis
- Supports proteomics, metabolomics, and environmental testing
- Fast data acquisition and high sensitivity
Applications
- Proteomics
- Metabolomics
- Environmental testing
- Drug discovery
- Food safety
- Forensic science
Product Specifications
PERFORMANCE
Mass Accuracy
- External calibration: <3 ppm RMS drift over 24 hours
- Internal lock mass calibration: <1 ppm RMS drift over 24 hours
- EASY-IC: <1 ppm RMS drift for at least 5 days
- <1 ppm mass accuracy levels with a single calibration for full mass range
Resolution
Up to 120,000 at m/z 200145
Sensitivity
Full Scan: < 3.0 fg reserpine on column
tMS2: < 3.0 fg reserpine on column
tSIM: < 1.5 fg reserpine on column
tMS2: < 3.0 fg reserpine on column
tSIM: < 1.5 fg reserpine on column
Speed
Up to 22 Hz at resolution setting at 15,000
Dynamic Range
>5000:1 within a single Orbitrap mass analyzer spectrum
>5,000 within a single Orbitrap mass analyzer spectrum
>5,000 within a single Orbitrap mass analyzer spectrum
MASS RANGE AND ANALYTE DETECTION
Mass Range
40 to 3000 m/z56
Standard mass range m/z 40–3,000
Standard mass range m/z 40–3,000
Detection Limit
< 3.0 fg reserpine on column
Detector
Independent Charge Detector
IONIZATION, SOURCE AND INTERFACE
Ionization Method
Electrospray ionization (ESI)
Heated electrospray ionization (H-ESI)
Heated electrospray ionization (H-ESI)
Ion Source
Thermo Scientific™ OptaMax™ NG ion source
Interface
Atmospheric pressure ionization (API) interface
Gas Flow and Requirements
- Source gas: High-purity nitrogen (>99% pure) at 600 ± 50 kPa (6.0 ± 0.5 bar, 87 ± 7 psi)
- A pre-regulator may be needed to maintain stable source gas pressure
- HCD collision gas: Ultra-high-purity nitrogen (UHP >99.999% pure) at 600 ± 50 kPa (6.0 ± 0.5 bar)
- For EASY-IC: Ultra-high-purity nitrogen (UHP >99.999% pure) at 600 ± 50 kPa (6.0 ± 0.5 bar)
MASS ANALYZER
Mass Analyzer
Orbitrap312
High-Field Orbitrap8
Thermo Scientific™ Orbitrap™ mass analyzer
High-Field Orbitrap8
Thermo Scientific™ Orbitrap™ mass analyzer
Quadrupole
Advanced quadrupole technology (AQT)
CHROMATOGRAPHY AND SAMPLE HANDLING
Chromatography
LC-MS
Sample Handling
- Supports flow rates from 1 to 1,000 µL/min for diverse sample introduction methods
- Includes heated electrospray ionization (H-ESI) source for enhanced performance
Injection System
Compatible with various liquid chromatography systems, allowing for flexible and efficient sample injection tailored to specific laboratory workflows.
DATA ACQUISITION AND ANALYSIS
Data Acquisition
High-speed real-time data acquisition and instrument control
Data Analysis
Thermo Scientific™ Orbitrap Exploris™ instrument control software
Thermo Scientific™ Xcalibur™ software
Thermo Scientific™ Xcalibur™ software
AUTOMATION AND SOFTWARE
Automation
Features ready-to-run method templates for various analytes and matrices
Drag-and-drop user interface to accelerate method development, enhancing laboratory automation.
Drag-and-drop user interface to accelerate method development, enhancing laboratory automation.
Software
Thermo Scientific™ Orbitrap Exploris™ instrument control software
Thermo Scientific™ Xcalibur™ software
Thermo Scientific™ Xcalibur™ software
OPERATIONAL FEATURES
Ease of Use
Single click calibrations
Drag-and-drop method setup
Predefined experiments driven by next-generation software
Drag-and-drop method setup
Predefined experiments driven by next-generation software
Maintenance and Durability
Designed for robust performance over hundreds of injections in complex sample matrices
Ensuring long-term durability and minimal maintenance requirements.
Ensuring long-term durability and minimal maintenance requirements.
Operating Conditions
Operating environment must be 18–27 °C (64–81 °F)
Relative humidity must be 20–80% with no condensation
Designed for indoor use at an altitude of up to 3,000 m (10,000 ft) above sea level
Relative humidity must be 20–80% with no condensation
Designed for indoor use at an altitude of up to 3,000 m (10,000 ft) above sea level
Power and Cooling
- 2× 208–240 Vac single phase, 15 A, 50/60 Hz, with earth ground for instrument and source vacuum pump
- 208–240 Vac single phase, 15 A, 50/60 Hz, with earth ground for the data system
- System averages 3,440 W (11,730 Btu/h) output for air conditioning needs
Dimensions and Footprint
534 × 763 × 703 mm (21 × 30 × 27.7 in)
120 kg (265 lb) without data system, vacuum rough pumps, and optional items
120 kg (265 lb) without data system, vacuum rough pumps, and optional items
GENERAL INFORMATION
Brand and Model
Thermo Scientific™, Orbitrap Exploris™ 120 mass spectrometer
Orbitrap Exploris 120 MS
Orbitrap Exploris 120 MS
Documentation and Support
Comprehensive operating manuals and product specifications are available, providing detailed guidance on system operation and maintenance.
Compatibility and Connectivity
- Seamless integration with Thermo Scientific software platforms: Xcalibur, Chromeleon CDS, and TraceFinder
- Ensures compatibility and connectivity within laboratory workflows
Configuration and Options
APCI/APPI probe for OptaMax NG ion source
Thermo Scientific™ FAIMS Pro Duo interface
Thermo Scientific™ FAIMS Pro Duo interface
Licensing and Certification
For Research Use Only
Not for use in diagnostic procedures
Not for use in diagnostic procedures
Cost and Operational Expenses
Pricing is available upon request from Thermo Fisher Scientific
A refurbished unit has been listed at $225,000
A refurbished unit has been listed at $225,000